Электронная медицинская библиотека Румедо.

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Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus

Дата публикации 22.10.2020
Автор: Benjamin M. Scirica, M.D., M.P.H., Deepak L. Bhatt, M.D., M.P.H., Eugene Braunwald, M.D., P. Gabriel Steg, M.D., Jaime Davidson, M.D., Boaz Hirshberg, M.D., Peter Ohman, M.D., Robert Frederich, M.D., Ph.D., Stephen D. Wiviott, M.D., Elaine B. Hoffman, Ph.D., Matthew A. Cavender, M.D., M.P.H., Jacob A. Udell, M.D., M.P.H., Nihar R. Desai, M.D., M.P.H., Ofri Mosenzon, M.D., Darren K. McGuire, M.D., Kausik K. Ray, M.D., Lawrence A. Leiter, M.D., and Itamar Raz, M.D., for the SAVOR-TIMI 53 Steering Committee and Investigators

The cardiovascular safety and efficacy of many current antihyperglycemic agents, including saxagliptin, a dipeptidyl peptidase 4 (DPP-4) inhibitor, are unclear.

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826

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High prevalence of previously unknown heart failure and left ventricular dysfunction in patients with type 2 diabetes

Дата публикации 22.10.2020
Автор: L. J. M. Boonman-de Winter & F. H. Rutten & M. J. M. Cramer & M. J. Landman & A. H. Liem & G. E. H. M. Rutten & A. W. Hoes

Aims/hypothesis The aim of this study was to assess the prevalence of (unknown) heart failure and left ventricular dysfunction in older patients with type 2 diabetes.

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876

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Chronic Kidney Disease and the Risk of End-Stage Renal Disease versus Death

Дата публикации 22.10.2020
Автор: Lorien S. Dalrymple, MD, MPH1, Ronit Katz, DPhil 2, Bryan Kestenbaum, MD, MS 3, Michael G. Shlipak, MD, MPH4,5, Mark J. Sarnak, MD, MS 6, Catherine Stehman-Breen, MD, MS 7, Stephen Seliger, MD, MS 8, David Siscovick, MD, MPH3,9, Anne B. Newman, MD, MPH10,11, and Linda Fried, MD, MPH10,11,12

In the United States, approximately one in three adults aged 65 years and older has chronic kidney disease (CKD), defined as an eGFR ...

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731

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Glycemic Durability of Rosiglitazone, Metformin, or Glyburide Monotherapy

Дата публикации 22.10.2020
Автор: Steven E. Kahn, M.B., Ch.B., Steven M. Haffner, M.D., Mark A. Heise, Ph.D., William H. Herman, M.D., M.P.H., Rury R. Holman, F.R.C.P., Nigel P. Jones, M.A., Barbara G. Kravitz, M.S., John M. Lachin, Sc.D., M. Colleen O’Neill, B.Sc., Bernard Zinman, M.D., F.R.C.P.C., and Giancarlo Viberti, M.D., F.R.C.P., for the ADOPT Study Group *

The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term glycemic control in type 2 diabetes is not known.

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724

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Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes

Дата публикации 22.10.2020
Автор: Bruce Neal, M.B., Ch.B., Ph.D., Vlado Perkovic, M.B., B.S., Ph.D., Kenneth W. Mahaffey, M.D., Dick de Zeeuw, M.D., Ph.D., Greg Fulcher, M.D., Ngozi Erondu, M.D., Ph.D., Wayne Shaw, D.S.L., Gordon Law, Ph.D., Mehul Desai, M.D., and David R. Matthews, D.Phil., B.M., B.Ch., for the CANVAS Program Collaborative Group

Canagliflozin is a sodium–glucose cotransporter 2 inhibitor that reduces glycemia as well as blood pressure, body weight, and albuminuria in people with diabetes. We report the effects of treatment with canagliflozin on cardiovascular, renal, and safety outcomes.

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801

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Prevalence of Low Glomerular Filtration Rate in Nondiabetic Americans: Third National Health and Nutrition Examination Survey (NHANES III)

Дата публикации 22.10.2020
Автор: Department of Medicine, McMaster University, Hamilton, Ontario; Department of Medicine, University of Western Ontario, London, Ontario; Health Research Methodology Graduate Program, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario; and Department of Medicine, Dalhousie University, Halifax, Nova Scotia

End-stage renal disease is an important and costly health problem. Strategies for its prevention are urgently needed. Knowledge of the population-based prevalence of renal insufficiency in nondiabetic adults would inform such strategies.

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648

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9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetesd2019

Дата публикации 22.10.2020
Автор: American Diabetes Association

The American Diabetes Association (ADA) “Standards of Medical Care in Diabetes” includes ADA’s current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care.

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1095

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National Kidney Foundation Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification

Дата публикации 22.10.2020
Автор: Andrew S. Levey, MD; Josef Coresh, MD, PhD; Ethan Balk, MD, MPH; Annamaria T. Kausz, MD, MS; Adeera Levin, MD; Michael W. Steffes, MD, PhD; Ronald J. Hogg, MD; Ronald D. Perrone, MD; Joseph Lau, MD; and Garabed Eknoyan, MD

Chronic kidney disease is a worldwide public health problem with an increasing incidence and prevalence, poor outcomes, and high cost. Outcomes of chronic kidney disease include not only kidney failure but also complications of decreased kidney function and cardiovascular disease.

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755

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Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients

Дата публикации 22.10.2020
Автор: E.A. Bohula, S.D. Wiviott, D.K. McGuire, S.E. Inzucchi, J. Kuder, K.A. Im, C.L. Fanola, A. Qamar, C. Brown, A. Budaj, A. Garcia‑Castillo, M. Gupta, L.A. Leiter, N.J. Weissman, H.D. White, T. Patel, B. Francis, W. Miao, C. Perdomo, S. Dhadda, M.P. Bonaca, C.T. Ruff, A.C. Keech, S.R. Smith, M.S. Sabatine, and B.M. Scirica, for the CAMELLIA–TIMI 61 Steering Committee and Investigators

Lorcaserin, a selective serotonin 2C receptor agonist that modulates appetite, has proven efficacy for weight management in overweight or obese patients. The cardiovascular safety and efficacy of lorcaserin are undefined.

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699

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Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach

Дата публикации 22.10.2020
Автор: SILVIO E. INZUCCHI, MD1 RICHARD M. BERGENSTAL, MD2 JOHN B. BUSE, MD, PHD3 MICHAELA DIAMANT, MD, PHD4 ELE FERRANNINI, MD5 MICHAEL NAUCK, MD6 ANNE L. PETERS, MD7 APOSTOLOS TSAPAS, MD, PHD8 RICHARD WENDER, MD9 DAVID R. MATTHEWS, MD, DPHIL10,

Position Statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

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817

Статьи

Артериальная гипертензия у взрослых

Дата публикации 22.10.2020
Разработчик клинической рекомендации: Российское кардиологическое общество

Артериальная гипертензия (АГ) — синдром повышения клинического артериального давления (АД) при гипертонической болезни и симптоматических АГ выше пороговых значений, определенных в результате эпидемиологических и рандомизированных контролируемых исследований, продемонстрировавших связь с повышением сердечнососудистого риска и целесообразность и пользу лечения, направленного на снижение АД ниже ...

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1054

Статьи

Особенности почечной патологии у больных сахарным диабетом 2 типа

Дата публикации 22.10.2020
Автор: М.Ш. Шамхалова, Н.П. Трубицына, Н.В. Зайцева, М.В. Шестакова

Сахарный диабет [СД] 2 типа относится к числу наиболее распространенных заболеваний.

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746

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Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and theEuropeanAssociation for the Study of Diabetes (EASD)

Дата публикации 22.10.2020
Автор: Melanie J. Davies,1,2 David A. D’Alessio,3 Judith Fradkin,4 Walter N. Kernan,5 Chantal Mathieu,6 Geltrude Mingrone,7,8 Peter Rossing,9,10 Apostolos Tsapas,11 Deborah J. Wexler,12,13 and John B. Buse14

The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the prior position statements, published in 2012 and 2015, on the management of type 2 diabetes in adults. A systematic evaluation of the literature since 2014 informed new recommendations. These include additional focus on lifestyle management and diabetes self-management education ...

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725

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Obesity and Diabetic Kidney Disease

Дата публикации 22.10.2020
Автор: Christine Maric-Bilkan, PhD. Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA

The prevalence of obesity (body mass index, BMI ≥ 30 kg/m2) has risen to epidemic proportions and continues to be a major health problem worldwide 1–3. The high prevalence of obesity is closely linked to the increased incidence of a number of chronic diseases, including type 2 diabetes, hypertension and cardiovascular disease 2, 4–8.

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1042

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Diabetes with early kidney involvement may shorten life expectancy by 16 years

Дата публикации 22.10.2020
Автор: Chi Pang Wen, Chia Hsuin Chang, Min Kuang Tsai, June Han Lee, Po Jung Lu, Shan Pou Tsai, Christopher Wen, Chien Hua Chen, Chih Wen Kao, Chwen Keng Tsao and Xifeng Wu

This study aimed to identify the excess risks associated with diabetic patients with early kidney involvement (early diabetic kidney disease). The mortality risks of early diabetic kidney disease, defined as diabetes in early stages 1-3 chronic kidney disease (CKD), were assessed from a cohort of 512,700 adults in Taiwan participating in a health surveillance program from 1994-2008. Three related ...

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